Does the Use of e-Cigarettes Contribute to Smoking Cessation?

Does the Use of e-cigarettes aid in smoking cessation | HealthSoul

Despite the well-documented health problems associated with smoking, millions still choose to embrace the habit. Even those who desire to quit find distancing themselves from the habit extremely challenging due to its addictive nature.

Many methods have been developed throughout the years in an attempt to aid people in their quest to quit smoking, all with varying degrees of success. To this day, new strategies are being implemented and tested.

Individual counseling has proven to be a relatively successful technique for encouraging smoking cessation. It has been theorized that the use of electronic cigarettes (e-cigarettes), especially in conjunction with individual counseling, may be effective in aiding cessation, as well. To test this controversial idea, researchers conducted a randomized clinical trial.

The Study

Does the Use of e-cigarettes aid in smoking cessation Study

376 participants were included in this study, all of whom were motivated to quit smoking. The trial took place at 17 Canadian sites between November 2016 and September 2019. Outcomes were reported through March of 2020.

The participants were randomly divided into three groups—one that would receive nicotine e-cigarettes, one that would receive non-nicotine e-cigarettes, and one that would receive no e-cigarettes. These groups contained 128, 127, and 121 participants, respectively. Individual counseling was given to all groups.
Researchers were looking for a primary endpoint of abstinence at 12 weeks and 24 weeks. If data was missing, it was assumed those participants were smoking. Secondary endpoints were also analyzed, including abstinence at follow-ups, adverse events, change in daily cigarette consumption, continuous abstinence, dropouts due to adverse effects, treatment of adherence, and serious adverse events.


Of the 376 participants included in the trial, 80% self-reported their smoking status at 12 weeks, and 74% self-reported their smoking status at 24 weeks.
Those in the nicotine e-cigarette and individual counseling group had higher rates of abstinence at 12 weeks and 24 weeks (21.9% and 17.2%) than the counseling alone group (9.1% and 9.9%). The same held true of the non-nicotine e-cigarette group (17.3% and 20.5%).

Adverse events were common in all groups, especially cough and dry mouth (64% and 53%). The nicotine e-cigarette group experienced adverse events at a 94% rate, the non-nicotine e-cigarette group at a 93% rate, and the counseling-only group at a 73% rate.

What it Means

While at face value the data seems to indicate that nicotine e-cigarettes with individual counseling are advantageous for adults that are motivated to quit smoking when compared to counseling alone, that advantage dips over time.

Because this trial was terminated early, and the findings were inconsistent, especially between nicotine and non-nicotine e-cigarettes, more research is needed to truly determine the potential value of incorporating e-cigarette use into a treatment plan that includes counseling.